Minimally Invasive Treatment of Worn Dentition With Innovative CAD-CAM Composites

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02828696

Enrollment

Registered

2016-07-12

Start date

2016-06-30

Completion date

2021-12-31

Last updated

2019-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Wear

Keywords

CAD-CAM composites, Worn dentition, minimally invasive treatment

Brief summary

This study evaluates the effectiveness of a minimally invasive treatment, consisting of partial polymer-infiltrated-ceramic-network (PICN) restorations, used in case of rehabilitation of advanced and generalized dental wear over a period of 5 years.

Interventions

DEVICENo prep treatment of worn dentition with CAD-CAM composite

Realization of minimally invasive prostheses in PICN (CAD-CAM composite)for worn dentition. Tooth tissues are preserved: no preparation is performed and ultra-thin restorations are CAD-CAM milled.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Patients presenting advanced and generalized worn dentition * All the posterior teeth (minus 2) present wear * All the anterior teeth (tooth n°13 to n°23) need palatal veneers

Exclusion criteria

* More than one missing tooth on each mandible * Patients with crown(s), bridge(s) or implant(s) * Patients with non-stabilized parodontite * Smoker * Patients suffering from : 1. Parkinson's Disease 2. Severe osteoarthritis 3. Spontaneous pain in the temporomandibular joints, shift of the mandible and an opening limit (25 mm) * Conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance, or unreliability

Design outcomes

Primary

Measure	Time frame	Description
Clinical evaluation of minimally-invasive treatment protocol of worn dentition	5 years	Clinical evaluation following FDI criteria
Quality of life evaluation of minimally-invasive treatment protocol of worn dentition	5 years	Quality of life questionnaires

Secondary

Measure	Time frame	Description
Toxicology evaluation of PICN restorations mechanical and biological behaviour	5 years	Toxicology ex vivo evaluation
Wear evaluation of PICN restorations mechanical and biological behaviour	5 years	Wear ex vivo evaluation

Countries

Belgium

Contacts

Primary ContactAmélie K Mainjot

a.mainjot@chu.ulg.ac.be

Backup ContactJulie Oudkerk

oudkerk.julie@gmail.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026