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Improvement of the Etiological Diagnosis of the Pericarditis

Improvement of the Etiological Diagnosis of the Pericarditis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02828085
Acronym
PERICARDITE
Enrollment
979
Registered
2016-07-11
Start date
2013-07-07
Completion date
2022-10-26
Last updated
2023-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective Pericarditis

Brief summary

Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis. The etiologies are very numerous and can be classified as infectious, neoplastic, metabolic or systemic, toxic causes. Diagnosis is difficult, and 80% of etiologies remain classified idiopathic. In their laboratory to improve the diagnosis of this syndrome investigators have developed a strategy of systematic prescription of biological tests by kit. This prescription by 'kit' strategy proved its interest by comparison with an intuitive requirement of biological. In this study investigators want to improve the diagnostic causative of pericarditis by implementing a new diagnostic strategy. This new strategy includes (i) samples additional less invasive for the patient, the swab pharyngeal and nasal, (ii) the addition of at the outset of more effective diagnostic techniques: specific Polymerase Chain Reaction (PCR)

Interventions

BIOLOGICALNasal swab

Nasal swab will be performed in addition to the routine diagnosis visit in order to determine the diagnosis of infective pericardite with a more specific technique: PCR

Sponsors

Assistance Publique Hopitaux De Marseille
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient prescribed with a pericarditis kit for etiological diagnosis of a pericardial syndrome. * Adult patient (= or \> 18 years old) * Patient who freely signed the informed consent form. * Patient affiliated to a health insurance regime

Exclusion criteria

* Minor patient ( age \<18 years) * Pregnant, parturient or breastfeeding woman * Adult patient incapable or unable to consent * Patient deprived of liberty under judgment * Person living in a health or social specialised structure * Person in vital emergency situation

Design outcomes

Primary

MeasureTime frame
Percentage of pericarditis whose etiological diagnosis has been established.1 day

Secondary

MeasureTime frame
Identification of the detected emerging pathogens among infectious causesof pericarditis1 day
Prevalence of the emerging pathogens: assessement of the percentage of emerging pathogens among the studied population1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026