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Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02827734
Enrollment
50
Registered
2016-07-11
Start date
2015-10-31
Completion date
2020-12-31
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Healthy Controls, Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Non-specific Interstitial Pneumonia, Sarcoidosis, Granulomatosis With Polyangiitis (Wegener's Disease)

Brief summary

Current diagnostic tools used in interstitial lung disease (ILD) do not meet the challenges set by the complex pathophysiology of this heterogenous group. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of patients with various ILDs.

Interventions

DEVICEmultiple breath washout tests

Sponsors

Universitätsmedizin Mannheim
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* known or suspected interstitial lung disease

Exclusion criteria

* pregnancy * inability to participate

Design outcomes

Primary

MeasureTime frame
lung clearance index (LCI) as determined by multiple breath washout30 minutes
airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry30 minutes

Secondary

MeasureTime frame
repeatability of lung clearance index (LCI)30 minutes

Countries

Germany

Contacts

Primary ContactFrederik Trinkmann, Dr.
frederik.trinkmann@umm.de+496213833879

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026