Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02827721

Enrollment

150

Registered

2016-07-11

Start date

2015-07-31

Completion date

2020-11-30

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD, Obstructive Ventilation Disorder, Pulmonary Emphysema

Brief summary

Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of COPD.

Interventions

DEVICEimpulse oscillometry

DEVICEmultiple breath washout test

DEVICEbody plethysmography

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* known or suspected COPD * known or suspected obstructive ventilation disorder * pulmonary healthy controls

Exclusion criteria

* pregnancy * inability to participate

Design outcomes

Primary

Measure	Time frame
lung clearance index (LCI) as determined by multiple breath washout	30 minutes
airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry	30 minutes

Secondary

Measure	Time frame
repeatability of lung clearance index (LCI)	30 minutes

Countries

Germany

Contacts

Primary ContactFrederik Trinkmann, Dr.

frederik.trinkmann@umm.de+496213833879

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026