Colorectal Cancer
Conditions
Keywords
IoC, monitor, elderly, postoperative effectiveness
Brief summary
The morbidity of colorectal cancer and the surgery number among elderly is growing. The investigators need to provide more advanced and specific monitoring technology for these patients. Index of consciousness (IoC) monitor is now widely used among endoscopy, cholecystectomy and other common clinical applications. The investigators goal is to verify whether using IoC monitor could help to improve the postoperative recovery after colorectal surgery.
Detailed description
Participants will be randomly assigned, in a 1:1 ratio, to receive IoC monitoring or BIS monitoring during the operation as the criteria for adjustment of analgesics use. The randomization sequence will be computer-generated, and randomization will be performed in blocks and will be stratified according to participating center. The number of dialysis and patient's recovery after the transplantation will be recorded. The participation of each patient is scheduled till they discharge from hospital.
Interventions
DEVICEAngel-6000D Multiparameter Anesthesia Monitor (IoC)
The Angel-6000D Multiparameter Anesthesia Monitor, Shenzhen Weihaokang Medical Technology Co., Ltd, Guangdong, China
DEVICEBIS VISTA Monitor (BIS)
BIS VISTA Monitor, Covidien, Changchun city shi jia trade co., Ltd, Changchun, China
Sponsors
First Affiliated Hospital Xi'an Jiaotong University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged over 60 years old that underwent Colorectal surgery in the First Affiliated Hospital of Xi'an Jiaotong University.
Exclusion criteria
* Having severe comorbidity history,for example,severe cardiac dysfunction * Having central nervous system disease, severe endocrine, and history of mental disorders * Alcoholic and long-term use of sedatives and opioids history * Drug allergy history.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration time in PACU | 24 hours | patients able to leave PACU with the proper Aldrete score |
Secondary
| Measure | Time frame |
|---|---|
| Use of remifentanil | during surgery |
| Use of propofol | during surgery |
| length of hospital stay (LOS) | Participants will be followed for the duration of hospital stay, an expected average of 2 weeks |
Countries
China
Contacts
Primary ContactJing Xu, MD
Backup ContactQiang Wang, PHD
Outcome results
None listed