A Prospective, Multicenter Registry With Targeted Temperature Management After Out-of-hospital Cardiac Arrest in Korea

Conditions

Out-of-Hospital Cardiac Arrest

Keywords

therapeutic hypothermia

Brief summary

Therapeutic hypothermia after out-of-hospital cardiac arrest is considered as a standard care. However, optimal candidates, optimal dose, duration, timing of initiation and rate of rewarming is still unknown. The objective of this project is to improve the outcomes for patients after resuscitation from out-of-hospital cardiac arrest treated with therapeutic hypothermia established from the analysis of multicenter registry data.

Kim YJ, Ko BS, Roh YI, Kim YH, Kim WY.

2025-04-11

10.1371/journal.pone.0319733

Different neuroprognostication thresholds of neuron-specific enolase in shockable and non-shockable out-of-hospital cardiac arrest: a prospective multicenter observational study in Korea (the KORHN-PRO registry)

Youn‐Jung Kim, Yong Hwan Kim, Chun Song Youn, In Soo Cho, Su Jin Kim et al. (10 authors)

Critical Care2023-08-0921 citations

10.1186/s13054-023-04603-6

Background frequency can enhance the prognostication power of EEG patterns categories in comatose cardiac arrest survivors: a prospective, multicenter, observational cohort study.

Kim YJ, Kim MJ, Kim YH, Youn CS, Cho IS, Kim SJ, Wee JH, Park YS, Oh JS, Lee DH, Kim WY, Korean Hypothermia Network Investigators.

2021-11-177 citations

10.1186/s13054-021-03823-y

Association between acute kidney injury and neurological outcome or death at 6 months in out-of-hospital cardiac arrest: A prospective, multicenter, observational cohort study.

Oh JH, Lee DH, Cho IS, Youn CS, Lee BK, Wee JH, Cha KC, Chae MK, Shin J, Korean Hypothermia Network Investigators.

2019-08-2813 citations

10.1016/j.jcrc.2019.08.029

Interventions

OTHERnot provided

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* age of older than 18 years * out-of-hospital cardiac arrest * comatose mentality after return of spontaneous circulation (ROSC) * treated with therapeutic hypothermia, regardless of target temperature

Exclusion criteria

* suspected or confirmed to cerebrovascular accident * poor pre-arrest neurologic status (CPC\>3) * patients who are terminally ill or for whom intensive care dose not seem to be appropriate * Do not attempt resuscitation (DNAR) order * patients with tympanic membrane temperature below 30 degree celsius on admission

Design outcomes

Primary

Measure	Time frame	Description
survival	6 months after cardiac arrest	—
Neurologic Outcome	6 months after cardiac arrest	Cerebral Performance Category (CPC). CPC 1,2 : Good Outcome CPC 3,4,5 : Poor Outcome

Secondary

Measure	Time frame	Description
survival	duration of hospitalization, limit 180 days	—
neurological outcome	duration of hospitalization, limit 180 days	Cerebral Performance Category (CPC). CPC 1,2 : Good Outcome CPC 3,4,5 : Poor Outcome
Survival	1 month after cardiac arrest	—

Countries

South Korea

Contacts

Primary ContactKyu Nam Park, MD, PhD

emsky@catholic.ac.kr82-2-2258-6301

Outcome results

None listed