Prediabetic State
Conditions
Brief summary
This pilot study seeks to demonstrate feasibility to conduct data collection and illustrate potential for effect of fractionalized bouts of stair climbing on glucose control in adults at risk for type 2 diabetes.
Detailed description
Objective: Compare the short-term effects of two different fractionalized stair climbing bout protocols on glucose control among adults at risk for type 2 diabetes. Rationale: Fractionalized physical activity is associated with reduced BMI, glycated hemoglobin, lower 2-hr plasma glucose and insulin sensitivity in cross-sectional studies. Yet, few studies have examined the effects of fractionalized or intermittent physical activity in a prospective manner. Furthermore, the research is limited to patients with diagnosed type 2 diabetes, or using exercise of a moderate intensity. The hypothesis is that stair climbing, a vigorous-intensity activity, may have a greater health effect. However, this has not been tested in short bouts of activity that are spread out during a day. Implications: Fractionalized physical activity may be more feasible for adults at risk for, or with diagnosed type 2 diabetes who are not currently active. These short bouts can increase energy expenditure throughout the day, rather than in one long continuous bout as currently recommended.
Interventions
BEHAVIORALStair Climbing Frequency
Includes 1 sedentary day prior to completing crossover phases.
Sponsors
University of Illinois at Urbana-Champaign
Jennifer Gay
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* Age greater than 40 years but less than 65 years (working age adult with reduce physiologic capacity to regulate glucose) * BMI of overweight or obese (25.0 to 35.0) * Answered No to all questions on the Physical Activity Readiness Questionnaire, or has physician approval to participate * Hemoglobin A1C% value in the at-risk range of 5.7 to 6.4
Exclusion criteria
* Unable to physically perform stair climbing * Currently exercising for 60 or more minutes weekly. * Weight over 275 lbs (because stair climbing machine has a weight limit)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Continuous Glucose Monitor | Up to 5 days | Participant has device inserted prior to dinner the night before the sedentary day, completes the sedentary day and two stair climbing days, then has the device removed on the morning of the 5th day. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart Rate | 2 Intervention Days | Measuring heart rate during stair climbing for % max heart rate and % heart rate reserve. Heart rate will be measured during the stair climbing bouts on each of the two intervention days. |
Countries
United States
Outcome results
None listed