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Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control

Clinical Evaluation of the Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control: A RCT

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02827305
Enrollment
36
Registered
2016-07-11
Start date
2015-08-31
Completion date
2015-08-31
Last updated
2016-07-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Diseases

Keywords

antiplaque, antigingivitis

Brief summary

This study evaluates the adjunctive use of Centella Asiatica (gotukola) to scaling in the reduction of plaque and gingival inflammation. Patients were divided into three groups of which group 1 received scaling and gotukola mouthwash, group 2 received scaling only and group 3 received gotukola mouthwash only.

Detailed description

Mechanical plaque control by tooth brushing is considered to be the ideal way of preventing plaque associated gingivitis. However due to various factors individuals fail to perform an adequate quality of self performed plaque control. Centella Asiatica (gotukola) possess wide range of biological activities like anti-inflammatory, anti-psoriatic, anti-ulcer, hepato-protective, anticonvulsant, immunostimulant, cardioprotective, antidiabetic, antiviral, antibacterial, antifungal, etc. So, it could be used as adjunctive to mechanical periodontal therapy.

Interventions

DRUGGotukola

10 ml of mouthwash to be rinsed for duration of 60 seconds

PROCEDUREScaling

Ultrasonic scaling was performed in one visit on both upper and lower arches.

Sponsors

Sri Hasanamba Dental College and Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
14 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* Minimum of 22 natural teeth * Participants with Chronic generalized gingivitis * Participants with plaque index score ≥1

Exclusion criteria

* Participants with fixed or removable appliances * Participants with more than full coverage restorations * Medically compromised participants * Participants on long term medications * Smokers * Participants who had used any type of antibacterial mouthwash in 4weeks of commencement. * Patients with history of recent periodontal therapy

Design outcomes

Primary

MeasureTime frameDescription
The efficacy of gotukola as an adjunct to scaling was assessed by using plaque index and gingival indes2-8-2015 to 16-8-2015A total of 36 patients were participated in the study and the outcome measures were assessed 15 days after the start of the study, PLaque index ( Silnes and Loe 1964) - The buccal, lingual,mesial and distal surfaces of the index teeth is given a scoring from 0-3 The scores from the four areas of the teeth are added and divided by four in order to give the plaque index of the tooth. The index for the patient is obtained by summing the indices for all six teeth and dividing by six. Gingival index -Loe and Silnes 1963- The buccal, lingual,mesial and distal surfaces of all ginival tissues of index teeth were given a scroe from 0-3.This then constitutes the GI for the area and scores from the 4 areas of the tooth are added and divided by four to give GI for the tooth. Scores for individual teeth may be grouped to designate the GI for the group of the teeth. The scores are added and divided by nu,ber of teeth to get GI for an individual

Countries

India

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026