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Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02826746
Enrollment
20
Registered
2016-07-11
Start date
2016-07-31
Completion date
2019-03-31
Last updated
2019-04-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Neoplasms

Brief summary

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy. The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

Interventions

DRUGMagnesium Sulfate

adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

DRUGNormal saline

the same bolus and infusion volumes of normal saline

Sponsors

Ajou University School of Medicine
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Thyroidectomy

Exclusion criteria

* Allergy to magnesium * Chronic pain * Chronic opioid use * Chronic NSAID use * Renal dysfunction * Liver dysfunction * Cardiac arrythmia * Seizure

Design outcomes

Primary

MeasureTime frameDescription
Throat painUp to 48 hours after surgery endpain assessment using visual analog scale

Secondary

MeasureTime frame
Fentanyl dose in recovery roomUp to 30 minutes after surgery end

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026