Breast Cancer
Conditions
Keywords
Algorithms, Image Processing, Computer-Assisted/methods*, Magnetic Resonance Imaging/methods*, Data Compression, Breast Neoplasms
Brief summary
Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different times. These curves profiles are designed to differentiate benign from malignant lesions. Recently, Mann et al, (2014) showed that increasing the temporal resolution of dynamic acquisitions; lesion enhancement curves over time were more accurate than the curves usually performed. It seems necessary to work on sequences having better temporal resolution without compromising however spatial resolution.
Interventions
OTHER3.0 Tesla in Magnetic Resonance Imaging
Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition. The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.
Sponsors
Institut de Cancérologie de Lorraine
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Patient to benefit a MRI in the assessment for a breast carcinoma * Age \>18 years old * Assessment on 3.0 Tesla in Magnetic Resonance Imaging * ECOG performance status ≤ 3 * Ability to provide an informed written consent form
Exclusion criteria
* Age \< 18 years old * Claustrophobia * Contraindication to the injection of gadolinium contrast medium * Contraindication to MRI * Persons deprived of liberty or under supervision
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Agreement between compressed sensing and standard image acquisition | 1 day | Agreement between compressed sensing and standard image acquisition is defined by percentage of lesions detected by both modes of acquisitions |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Analysis of dammage contours | 1 day | Analysis of lesions contours will be performed according to Bi-RADS classification |
| Image quality in compressed sensing acquisition | 1 day | The image quality will be evaluated using a quality scale |
Countries
France
Outcome results
None listed