Bronchial Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Conditions
Brief summary
Current diagnostic tools used in pulmonary disease often do not meet the challenges set by the respective pathophysiology. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of patients with various pulmonary diseases.
Interventions
DEVICEimpulse oscillometry (IOS)
DEVICEbody plethysmography (BP)
DEVICEquantitative computed tomography (qCT)
ultra-low-dose qCT
Sponsors
Universitätsmedizin Mannheim
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* known or suspected pulmonary lung disease * indication for computed tomography
Exclusion criteria
* pregnancy * inability to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| correlation of lung clearance index (LCI) as determined by multiple breath washout with emphysema quantification as determined by qCT | 2 weeks |
| correlation of airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry with emphysema quantification as determined by qCT | 2 weeks |
| correlation of residual volume and airway resistance as determined by body plethysmography with and emphysema quantification as determined by qCT | 2 weeks |
Countries
Germany
Contacts
Primary ContactFrederik Trinkmann, Dr.
Outcome results
None listed