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Observing Changes in Ventilation Pattern During Procedural Sedation

Observing Changes in Ventilation Pattern During Procedural Sedation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02825433
Enrollment
160
Registered
2016-07-07
Start date
2013-08-31
Completion date
2015-03-31
Last updated
2016-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Ventilation

Brief summary

The ventilation (respiratory rate, tidal volume and end-tidal CO2) was monitored for patients receiving procedural sedation during endoscopy procedures in order to observe what changes commonly occur.

Detailed description

The literature does not currently describe which ventilation changes a clinician should watch for to keep a patient safe during procedural sedation provided by fentanyl and propofol. This observational study aimed to record the breath-by-breath respiratory rate, tidal volume and end-tidal CO2 for each patient during procedural sedation for each endoscopy procedure. Data analysis offline will aim to identify any patterns in ventilation which may precede apnea or blood oxygen desaturation. The patterns in ventilation preceding apnea or blood oxygen saturation will be compared and contrasted with the patterns of ventilation during normal ventilation periods.

Interventions

OTHERNo intervention, only ventilation monitoring

Sponsors

University of Utah
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* (i) ASA I, II, or III * (ii) patients older than eighteen * (iii) English speaking * (iv) undergoing a colonoscopy procedure and receiving procedural sedation

Exclusion criteria

* (i) inability/refusal of subject to provide informed consent * (ii) standard colonoscopy

Design outcomes

Primary

MeasureTime frame
Respiratory rateMeasured for every breath observed throughout the endoscopy procedure
Tidal volumeMeasured for every breath observed throughout the endoscopy procedure
End-tidal CO2Measured for every breath observed throughout the endoscopy procedure

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026