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Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02825121
Acronym
CurHaTOF
Enrollment
60
Registered
2016-07-07
Start date
2016-02-29
Completion date
2017-09-30
Last updated
2017-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adductor Pollicis, Flexor Hallucis, Observation of Neuromuscular Block

Brief summary

Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist. However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient. To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist. The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention. The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis. The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis. This is a prospective, exploratory, uncontrolled, single-center for routine care. Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

Interventions

DEVICEMonitoring Neuromuscular Blockade the Flexor Hallucis
DEVICEMonitoring Neuromuscular Blockade adductor of the thumb.

Sponsors

Poitiers University Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* over 18 years * Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time. * ASA I or II patients * free subject, without guardianship or subordination * No opposition given by the patient after information

Exclusion criteria

* under 18 years * known neuromyopathy * Diabetics * Emergency surgery and a full stomach * predictable difficult intubation * Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception

Design outcomes

Primary

MeasureTime frame
Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis1 day

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026