Chronic Obstructive Pulmonary Disease, Hypogonadism
Conditions
Keywords
hypogonadism, Chronic Obstructive Pulmonary Disease, Severity of Illness Index, Testosterone
Brief summary
The Aims of the study are estimate the association between the severity of COPD and free testosterone level and the prevalence of hypogonadism in adult men with stable COPD
Interventions
None listed
Sponsors
Asociacion Argentina Medicina Respiratoria (AAMR)
Hospital Italiano de Buenos Aires
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
MALE
Age
45 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults Men ≥ 45 years * COPD defined according to clinical diagnosis and spirometry American thoracic society ( ATS) criteria * Stable COPD without recent acute exacerbation (less than 2 weeks)
Exclusion criteria
* Refusal to participate or informed consent process * Those who are under treatment with testosterone replacement or anti-androgens * Comorbidities: Cirrhosis, Alcoholism, cryptorchidism, panhypopituitarism, Pituitary adenoma. * Orchiectomy * Systemic glucocorticoids (equivalent dose ≥ 4 mg of prednisone in the last 3 weeks). * Relative and absolute contraindications for spirometry.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Free testosterone Level | One day |
Secondary
| Measure | Time frame |
|---|---|
| Prevalence of Hypogonadism | One day |
Countries
Argentina
Contacts
Primary ContactHoracio M Castro, MD
Backup ContactJoaquin Maritano Furcada, MD
Outcome results
None listed