Neonatal Respiratory Distress Syndrome
Conditions
Brief summary
Respiratory distress is one of the first hospital grounds during the neonatal period. The clinical presentation and severity vary by gestational age and cause. She reports to various etiological factors as maternal, neonatal or sometimes entangled. The symptomatic management has benefited from organizational progress (perinatal care) and techniques, including antenatal steroids, the use of exogenous surfactant and non-invasive ventilation early, so that the use of intubation is less frequent. The short-term evolution of patients with early respiratory distress is based on gestational age, cause and initial management.
Detailed description
Main objective: To describe the care and short-term respiratory become newborns 32 weeks gestation or older with early and persistent respiratory distress to 2 hours of life (H2) over a period of one year in a type IIb motherhood. Methodology : Design: retrospective, descriptive, single-center, non-interventional Performed in the Saint Joseph neonatal unit. Study duration: 1 year (01/05/2013-04/30/2014). Acquisition of data: The patients were selected from the hospitalization reports of infants by taking the following key words: respiratory distress, invasive and noninvasive ventilation, intubation, exogenous surfactant, pneumothorax. Data collected: * Obstetric data: * Mode of delivery: route of delivery, presentation at birth. * Maternal morbidity. * antenatal corticosteroids in infants less than 34 weeks. * Neonatal data: * Gestational Age * Birth Weight * cord pH * Apgar M5 * The terms of the allocation: * Tracheal Intubation * ventilation modes (controlled mechanical ventilation (VMC), non-invasive ventilation (NIV), nasal cannula), the maximum reached FiO2 (fraction of inspired oxygen), ventilation time for each ventilation mode. These different methods were studied in the delivery room during hospitalization (in intensive care and neonatal intensive care NICU). * The place of hospitalization: resuscitation and / or NICU. * The transfer to the NICU resuscitation if necessary. * Received drugs (exogenous surfactant, antibiotics, caffeine) * The successful primary diagnosis.
Interventions
OTHERNo intervention. It's a description study
Sponsors
Fondation Hôpital Saint-Joseph
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
32 Weeks to 40 Weeks
Healthy volunteers
No
Inclusion criteria
* Gestational Age (A) ≥ 32 SA * Birth weight (PN) ≥ 1000 g * Respiratory distress appeared in the first 2 of life and non-limiting in H2.
Exclusion criteria
* AG \<32 SA * PN \<1000g * Malformation diagnosed ante or immediate postpartum justifying a specific urgent care. * Respiratory distress appeared before H2 and H2-limited before, whatever the company therapeutic. * Respiratory distress appeared after H2.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Obstetric data | Day 0 | Number of Participants With same characteristics for: * Mode of delivery: route of delivery, presentation at birth. * Maternal morbidity. * antenatal corticosteroids in infants less than 34 weeks. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Neonatal data | Day 0 | Number of Participants With same characteristics for: * Gestational Age * Birth Weight * cord pH * Apgar M5 |
| The terms of the allocation: | Day 0 | Number of Participants With same characteristics for: * Tracheal Intubation * ventilation modes (controlled mechanical ventilation (VMC), non-invasive ventilation (NIV), nasal cannula), the maximum reached FiO2, ventilation time for each ventilation mode. These different methods were studied in the delivery room during hospitalization (in intensive care and neonatal intensive care NICU) * The place of hospitalization: resuscitation and / or NICU. * The transfer to the NICU resuscitation if necessary. * Received drugs (exogenous surfactant, antibiotics, caffeine) * The successful primary diagnosis. |
Countries
France
Outcome results
None listed