Benign Prostatic Hyperplasia, Prostate Cancer
Conditions
Keywords
Transurethral resection of the prostate, Anticoagulants, Platelet aggregation inhibitors
Brief summary
Benign prostatic hyperplasia(BPH) is a common disease in urology among old men. If BPH symptom cannot be controlled by drugs, then transurethral resection of the prostate (TURP), is recommended. Although the procedure is quit safe, these old men often take anticoagulants and antiplatelets to control cardiovascular diseases, which arose some concerns for their bleeding risk. The management of anticoagulation in patients undergoing surgical procedures is challenging because interrupting anticoagulation increases the risk of thrombotic events. At the same time, surgery and invasive procedures have associated bleeding risks that are increased by the anticoagulant administration. Now, the recommendation about anticoagulants and antiplatelets discontinuation had no concrete evidence, especially in TURP. Furthermore, there is no relative studies done in Taiwan population, which calls for further investigation.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* Admitted to National Cheng Kung University Hospital Urology during the study * Older than 20 years old * Agree to participate this study * Receiving transurethral resection of the prostate for benign prostatic hyperplasia or prostate cancer
Exclusion criteria
* Poor expression ability and without close care givers to answer questions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative blood transfusion | in 1 week after surgery |
| Bladder clots | in 10 days after surgery |
| Hematuria | in 10 days after surgery |
| Urine tract infection | in 10 days after surgery |
| Duration of catheter | in 10 days after surgery |
| Duration of hospitalization | in 1 week after surgery |
| Cardiovascular event | In 28 days after surgery |
| Major bleeding | In 28 days after surgery |
Countries
Taiwan