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Impact of Anticoagulants and Antiplatelets in Patients on Transurethral Resection of the Prostate

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02822963
Enrollment
0
Registered
2016-07-06
Start date
2016-03-31
Completion date
2016-08-31
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Prostatic Hyperplasia, Prostate Cancer

Keywords

Transurethral resection of the prostate, Anticoagulants, Platelet aggregation inhibitors

Brief summary

Benign prostatic hyperplasia(BPH) is a common disease in urology among old men. If BPH symptom cannot be controlled by drugs, then transurethral resection of the prostate (TURP), is recommended. Although the procedure is quit safe, these old men often take anticoagulants and antiplatelets to control cardiovascular diseases, which arose some concerns for their bleeding risk. The management of anticoagulation in patients undergoing surgical procedures is challenging because interrupting anticoagulation increases the risk of thrombotic events. At the same time, surgery and invasive procedures have associated bleeding risks that are increased by the anticoagulant administration. Now, the recommendation about anticoagulants and antiplatelets discontinuation had no concrete evidence, especially in TURP. Furthermore, there is no relative studies done in Taiwan population, which calls for further investigation.

Interventions

None listed

Sponsors

National Cheng-Kung University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Admitted to National Cheng Kung University Hospital Urology during the study * Older than 20 years old * Agree to participate this study * Receiving transurethral resection of the prostate for benign prostatic hyperplasia or prostate cancer

Exclusion criteria

* Poor expression ability and without close care givers to answer questions

Design outcomes

Primary

MeasureTime frame
Perioperative blood transfusionin 1 week after surgery
Bladder clotsin 10 days after surgery
Hematuriain 10 days after surgery
Urine tract infectionin 10 days after surgery
Duration of catheterin 10 days after surgery
Duration of hospitalizationin 1 week after surgery
Cardiovascular eventIn 28 days after surgery
Major bleedingIn 28 days after surgery

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026