Refractory Neoplasms
Conditions
Keywords
Ultrasonography-guided Laser Ablation
Brief summary
The purpose of this study is to evaluate the safety and efficacy of ultrasonography (US) -guided laser ablation liver, kidney, pancreas, lung and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.
Interventions
PROCEDUREUS-guided laser ablation for refractory neoplasms
Sponsors
First Affiliated Hospital of Zhejiang University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Patients with small hepatocellular carcinoma (single or multiple nodules of less than 3 cm in diameter), * Patients with Child-Pugh A/B, * Patients with PLT ≥ 50\*10E9/L and PT ≤ 20s.
Exclusion criteria
* Patients with blood coagulation dysfunction, ChildPugh ≥3, severe cardiopulmonary disease, intolerant anesthesia and upper gastrointestinal bleeding in shock.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 100 patients of refractory neoplasms with image-guided laser ablation-related effectivity as assessed by MRI | up to 24 months |
Countries
China
Contacts
Primary ContactTian'an Jiang, Phd
Backup ContactGuo Tian, Master
Outcome results
None listed