Physical Endurance
Conditions
Keywords
Neuromuscular, Supplementation, Elderly
Brief summary
The purpose for this study is to determine if beta-alanine supplementation combined with endurance-based resistance training can increase gains in muscular endurance to a greater extent than endurance-based resistance-training alone in older adults.
Interventions
Sponsors
University of Miami
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
60 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* 60-90 years of age * Living independently (not residing in an assisted living facility) * Through testing are found not to have sarcopenia * Gait speed \> 1 m/s * Skeletal Muscle Index \> 37% in men and \> 27.6 % in women *
Exclusion criteria
* Responding with a yes to any question on the PAR-Q. * Are currently pregnant, or plan to try and become pregnant during the study * Functional impairments that could impede the person's ability to participate in a resistance training program * Current or recent use of supplements (within the past 3 months for non-alanine containing supplements or one year for supplements containing beta-alanine). Individuals taking only basic multivitamins (without any herbal co-ingredients) may still be allowed to participate. These situations will be reviewed on a case-by-case basis. * Are currently enrolled in a regular exercise program (more than once per week) * Current or recent smoker * Use of medication containing corticosteroids * Mini-mental score of 21 or below * Severe musculoskeletal impairment * Uncontrolled chronic disease * Major depression * Severe vestibular problems
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Performance of Daily Activities | baseline, 12 weeks | Short Physical Functional Performance test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Body Fat | baseline, 12 weeks | Body fat assessment via bioimpedance |
| Change in Muscular Endurance | baseline, 12 weeks | 20 repetitions to measure decline in muscular power across repetitions |
| Change in Muscular Strength | baseline, 12 weeks | Maximal weight that could be lifted one time (1RM) |
Countries
United States
Outcome results
None listed