Cardiac Complications
Conditions
Brief summary
The hypothesis implies that this work is the use of hyperoxia during cardiopulmonary bypass by his heart preconditioning effect is associated with a lower incidence of cardiac arrhythmias (atrial fibrillation, tachycardia or ventricular fibrillation) and lesions of myocardial ischemia-reperfusion injury in cardiac surgery postoperative.
Interventions
DRUGmedical oxygen
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Major patient ≥ 18 years * Patient operated cardiac surgery for myocardial revascularization (CABG) or surgical correction of valvular or combined surgery (CABG and valve disease) or ascending aortic surgery * Signed Consent * Affiliation to social security
Exclusion criteria
* Permanent atrial fibrillation * Cordarone therapy, * Pregnant woman * Patient under guardianship or trusteeship or private public law * Internal pacemaker * Hypothermia, * Patient refusal, * Cardiac surgery without extracorporal circulation (ECC), * Participation in another study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurred within 15 days after surgery, disorders of heart rhythm (atrial fibrillation, tachycardia or ventricular fibrillation) | 15 days after surgery |
Countries
France
Outcome results
None listed