Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures

Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures: Near-infrared Spectroscopy (NIRS) Coupled to Electroencephalography (EEG)

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02819427

Acronym

Absence

Enrollment

Registered

2016-06-30

Start date

2013-04-30

Completion date

2018-08-31

Last updated

2018-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epilepsy

Keywords

Spectroscopy, Near-Infrared, Electroencephalography, children

Brief summary

This study, conducted in children with typical or atypical absence epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures without the need for any additional examination. This examination will be performed by combining near-infrared spectroscopy (NIRS) optical imaging and Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording. Surface electroencephalography (EEG) is a valuable tool to assess neuronal dysfunction from a functional point of view and is used in the routine follow-up of epileptic children. Optical imaging is a recent and promising medical imaging technique, which uses near-infrared light. This rapid, noninvasive and harmless quantitative technique can be easily used at the child's bedside or in the ward and provides metabolic information on brain functioning.

Interventions

DEVICENear Infra Red Spectroscopy (NIRS)

DEVICEElectroencephalography (EEG)

Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

3 Years to 14 Years

Healthy volunteers

Inclusion criteria

* Children aged 3 to 14 years * Featuring absence epilepsy with typical or atypical seizures characterized by the presence of spontaneous spike-wave flashes with standard EEG

Exclusion criteria

* All children with severe congenital malformation * Any refusal of a parent or child * Any child with a serious deterioration in the general condition and vital functions * Any child with dermatitis of the face or scalp * Children under 3 years old or over 14 years

Design outcomes

Primary

Measure	Time frame	Description
haemodynamic changes	Day 0	haemodynamic changes by optical imaging, during the 4 interictal, preictal, ictal and postictal phases of absence seizures as defined by EEG analysis

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026