Endemic and Emerging Diseases in Populations of Homeless
Conditions
Brief summary
Hypothesis: Homeless people have infections not diagnosed with a potential impact on their health status. Main Purpose: Improve the etiological diagnosis of endemic and/or emerging pathologies among homeless people.
Detailed description
In Marseilles, the population of homeless is estimated at 1500 individuals, including 800 usually sleeping in the street, 600 in foster homes and a hundred in the structures of care. The precarious living conditions of homeless persons promote the emergence or re-emergence of many communicable infectious diseases homeless people whose symptoms are often overlooked by the subject and rarely established etiologic diagnosis. Among these diseases, frequently described in the literature are infestation by lice and infectious diseases that they transmit (Bartonella quintana), skin infections, hepatitis E and C and finally the infection with Tropheryma Whipplei. In this study we propose to systematically in homeless subject an etiological diagnosis of pathogens at the origin of these diseases (i) to improve knowledge (ii) to improve their management, (iii) to limit the contagion.
Interventions
OTHERSwabs skin, pharyngeal, and blood sample
Collection of one blood sample with a volume of 10 mL (2 tubes of blood 5 mL ) and 2 swabs ( throat and skin ).
OTHERCollection of body lice
For the subjects infested with body lice , if they want, their underwear will be recovered and sent to the laboratory to measure the resistance to permethrin.
Sponsors
Assistance Publique Hopitaux De Marseille
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Homeless Subject on the day of the study in one of two shelters for homeless Marseille ( Madrague City and Forbin ) * Major subject ( \> or equal to 18 years) * Freely about having signed the written informed consent, * About affiliated with a social security scheme
Exclusion criteria
* Minor Subjects ( \< 18 years ) * Major subject under guardianship (L. 1121-8 ) * Subject privated of freedom or under court order (L. 1121-6 ) * Subject refusing to sign the informed consent form , * Subject not affiliated with a social security insurance * Pregnant women , parturient or nursing (L. 1121-7 ) .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of subjects with an established microbiological diagnosis | 3 years |
Secondary
| Measure | Time frame |
|---|---|
| Prevalence of Tropheryma whipplei infections | 1 day |
| Prevalence of infestation by body lice | 1 day |
| Prevalence of skin infections | 1 day |
| Prevalence of infections by Bartonella quintana | 1 day |
| Prevalence of infection by hepatitis E and C | 1 day |
| Percentage of body lice resistant to permethrin | 1 day |
Countries
France
Outcome results
None listed