Postoperative Pain
Conditions
Brief summary
Pain relief in knee Arthroscopic Surgery is essential for rapid recovery of function.
Detailed description
Intra-articular analgesia is useful in reducing patients' postoperative disability. It anticipates and prevents the onset of pain, and helps avoid the need for additional drugs. Usually it is possible to reach good analgesia in the immediate postoperative period by the administration of analgesic drugs. Recently, intra-articular administration of different anaesthetic substances with a local action (e.g. bupivacaine) has been introduced in clinical practice. The aim of the administration of these substances should not be the reduction of postoperative pain, but its prevention.
Interventions
DRUGDexamethasone
patients will receive intra-articular 8 mg dexamethasone added to 18 mL 0.25% bupivacaine into the knee joint.
DRUGDexmedetomidine
patients will receive intra-articular 1ug/kg dexmedetomidine added to 18 mL 0.25% bupivacaine into the knee joint.
DRUGSaline
patients will receive intra-articular 18 mL 0.25% bupivacaine and 2mL isotonic saline into the knee joint.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Patients scheduled for knee arthroscopy under spinal anaesthesia
Exclusion criteria
* Diabetes Mellitus * Contraindication to spinal anesthesia * Patient refusal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain free time | 48 hours | VAS |
Countries
Egypt
Outcome results
None listed