Infant, Premature
Conditions
Keywords
voice recognition
Brief summary
Many cognitive functions in humans are based on asymmetrical brain networks. For example, in most adults, the language is essentially processed by the left hemisphere, while other auditory functions, such as voice recognition, tend to be processed by the right hemisphere. Many studies, especially those conducted by Ghislaine Dehaene's team, have demonstrated the presence of anatomical and functional asymmetries by the first months of life. What are the causes of these asymmetries? How do they develop? Are they necessary for functioning or effective learning? This study, conducted in collaboration with the Compiègne applied mathematics team (Abdelatif El Badia) and the INSERM team (Ghislaine Dehaene), is designed to determine the stage of development at which hemispheric dominance for voice recognition is first observed and to identify the brain structure involved in preterm neonates whose sound environment is usually very different from that of the foetus. The impact of this environment on the infant's brain development and early learning will be evaluated.
Interventions
DEVICEelectroencephalogram (HR-EEG)
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
0 Days to 6 Days
Healthy volunteers
Yes
Inclusion criteria
* The distribution of children in the different groups of infants included in the study will be validated at the time of the acquisitions. * Normal group of children: A child meets the age criteria and without ductus arteriosus persistence ultrasound or detectable neurological disorders after clinical, neurophysiological and radiological (ETF, Scanner, MRI). * Group of children meet the age criteria and with cerebral neurological pathology detectable after clinical, neurophysiological and radiological (ETF, Scanner, MRI).
Exclusion criteria
About history: * All children with severe congenital malformation Regarding the study period; * Any refusal of a parent * Children with severe impairment of the general condition and vital functions * Children with dermatitis of the face or scalp * Children treated with ventilation High Frequency (HFO) * Presence of intravenous access on the scalp (preventing the realization of the ETF, EEG and NIRS
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The difference in amplitude | 10 weeks | The difference in amplitude of the electrical hemodynamic responses to stimuli depending on the conditions, which corresponds to the evoked potential mismatch Response |
| The difference in latency | 10 weeks | The difference in latency of the electrical hemodynamic responses to stimuli depending on the conditions, which corresponds to the evoked potential mismatch Response |
Countries
France
Outcome results
None listed