Impact of Physical Activity on Patients With Chronic Kidney Disease Not Receiving Dialysis Followed in the TIRCEL Network. An Exposed / Unexposed Study (PHYSALYS)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02818010

Acronym

PHYSALYS

Enrollment

259

Registered

2016-06-29

Start date

2012-05-31

Completion date

2015-10-31

Last updated

2016-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Insufficiency, Chronic

Keywords

physical activity, chronic kidney disease, nephrology, stage 3, stage 4, stage 5

Brief summary

PHYSALYS is an observational multicenter study. It's an analytical study comparing 2 groups: patients exposed to physical activity and unexposed. The main objective of the study is to compare the evolution of glomerular filtration rate at inclusion and 12 months later between patients practicing physical activity and patients not practicing. If necessary, the renal disease-related complications, which are not influenced by physical activity: (type of kidney disease, age and tobacco), would be taken into account. TIRCEL patients with chronic kidney disease (CKD) at stages 3, 4 or 5 can be included in the study. Their serum creatinine data, 12 months prior to inclusion, is collected retrospectively. Patients are followed in the trial during 12 months. To evaluate physical activity, patients respond to Global Physical Activity Questionnaire 2 (GPAQ2) at inclusion and 12 months later. During this 12 months period, the same biological data are collected prospectively.

Interventions

OTHERGlobal Physical Activity Questionnaire

The practice of physical activity is measured by the GPAQ 2 questionnaire (Global Physical Activity Questionnaire) developed by the World Health Organization.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Members of TIRCEL (Traitement de l'Insuffisance Chronique en rhônE-aLpes) network for over a year and having at least two measurements of glomerular filtration rate with an interval of 9 to 12 months between the first and the last measurement * Patients in stages 3, 4 or 5 of CKD * No dialysis CKD patients * Non transplanted CKD patients * Patients seeing nephrologist * Patients agreeing to be contacted for a phone call half an hour * Adults patients (\> 18 years) * Patients not living in institution * Patients being able to answer a questionnaire

Exclusion criteria

* Patients followed in the TIRCEL (Traitement de l'Insuffisance Chronique en rhônE-aLpes) network for less than one year or having less than 2 measurements of glomerular filtration rate with an interval of least 9 months or over 12 months between the first and the last measurement * Patients in stages 1 or 2 of CKD * CKD patients receiving dialysis * Transplanted CKD patients * Patients not seeing nephrologist * Patients refusing to be contacted for a phone call half an hour * Patients \< 18 years * Patients living in institution * Patients unable to answer a questionnaire

Design outcomes

Primary

Measure	Time frame	Description
Change of the Glomerular Filtration Rate (GFR)	Month 0, Month 12	The Glomerular Filtration Rate (GFR) annual slope between inclusion (M0) and 12 months (M12) after inclusion in exposed and unexposed groups.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026