Abdominal Surgery
Conditions
Keywords
∆POP: variation of the plethysmographic waveform of pulse oximetry, ∆PP: pulse pressure variation, pulse oximetry plethysmographic, abdominal surgery
Brief summary
The waveform plethysmographic signal can be used to establish an index for predicting fluid responsiveness (∆POP: respiratory variation of the plethysmographic waveform of pulse oximetry). This index was validated in some studies and because of its non-invasiveness it seems very interesting in anesthesia. However, in a previous study the investigators evaluated the correlation between the results provided by this index (∆POP) and those of the reference index (∆PP: pulse pressure variation), and the obtained results were significantly lower than what had been previously described. In this study, the index was calculated from a recording of a filtered signal. This unavoidable application of a filter on anesthesia monitors could contribute to the discrepancy between the ∆POP and the ∆PP. The realization of a new study, comparing ∆PP and ∆POP obtained from an unfiltered plethysmographic signal, should answer the ∆POP ability to be used in place of ∆PP.
Interventions
None listed
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hospital patient in general surgery and digestive department * Adult * Digestive sus mesocolic surgery with direct abdominal approach justifying a semi-invasive hemodynamic monitoring by arterial catheterization (liver, pancreatic, gastric and duodenal surgery) * Surgical approach by laparotomy * Patient under general anesthesia with mechanical ventilation * Agreeing to participate in the study after receiving information note
Exclusion criteria
* Known left systolic ventricular and/or diastolic failure * Arrhythmias * Surgery performed with thoracic approach * Surgery by laparoscopy * Emergency surgery * Hypersensitivity or allergic to any of the product used for usual anesthesia, hypersensitivity to soya or egg lecithin * Personal or familial history of malignant hyperthermia * Severe kidney impairment (creatinin clearance \<30ml/min) * Patients who participated in the previous month to another study protocol * Pregnant women or nursing * Under-age
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ∆PP: pulse pressure variation | Day 0 | reference index measured during abdominal surgery |
| ∆POP: respiratory variation of the plethysmographic waveform of pulse oximetry | Day 0 | noninvasive index obtained from plethysmographic raw signal measured during abdominal surgery |
Outcome results
None listed