Research on Anxiety and Depression: Computer-Assisted Therapy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02817438

Acronym

RADCAT

Enrollment

136

Registered

2016-06-29

Start date

2016-06-30

Completion date

2018-03-31

Last updated

2019-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety Disorders, Mood Disorders

Brief summary

This study examines how online self-guided programs can improve mood and anxiety symptoms. These programs use exercises from Cognitive-Behavioral Therapy, which is an evidence-based treatment for depression and anxiety. The purpose of this study is to learn who will do best with the online format. Our aim is to learn for whom online self-guided interventions are most efficacious. This knowledge is important because it will help inform clinicians and patients about who might benefit from this type of intervention versus who would need the assistance of a therapist. More specifically, we hope to figure out who would benefit from solely an online intervention and who would benefit from an online intervention in addition to other treatment.

Interventions

BEHAVIORALGood Days Ahead

Good Days Ahead is a web-based program based on the principles of Cognitive Behavioral Therapy (CBT). It can be used to supplement traditional psychotherapy, or as a stand-alone intervention. There are 9 lessons that address Thinking Skills, Behavioral Skills, Schemas, and Coping Tools. Lessons include videos from expert therapists and a Practice Section in which patients complete forms for self-monitoring symptoms and challenging negative thoughts.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Previous participation in the RAD study in our laboratory RAD study inclusion criteria are: * 18+ years of age * Fluent and literate in English * Can provide informed consent * fMRI scanning eligibility, including no evidence of any form of metal embedded in the body (e.g., metal wires, nuts, bolts, screws, plates, sutures)

Exclusion criteria

* Anyone who has not already completed the RAD study will be excluded. RAD study

Design outcomes

Primary

Measure	Time frame	Description
Depression and Anxiety Composite Score	12 weeks	Composite score combining 3 measures of depression and/or anxiety (PHQ-9, BAI, DASS)

Secondary

Measure	Time frame	Description
Quality of Life	12 weeks	WHOQOL scale

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026