Refractory Neoplasms
Conditions
Keywords
Endoscopic ultrasonography, Laser ablation
Brief summary
The purpose of this study is to evaluate the safety and efficacy of endoscopic ultrasonography (EUS) guided laser ablation liver, pancreas, and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.
Interventions
PROCEDUREEUS-guided laser ablation for refractory neoplasms
Sponsors
First Affiliated Hospital of Zhejiang University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Patients with refractory neoplasms including small hepatocellular carcinoma adjacent to the gastrointestinal tract, pancreatic neuroendocrine tumor, retroperitoneal tumor with less than 3 cm in diameter; * Patients with Child-Pugh A/B; * Patients with PLT ≥ 50\*10E9/L and PT ≤ 20s.
Exclusion criteria
* Patients with severe cardiopulmonary disease, intolerant endoscopy and anesthesia, upper gastrointestinal bleeding in shock, corrosive esophagitis and acute gastritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 80 patients of refractory neoplasms with EUS-guided laser ablation-related effectivity as assessed by MRI | up to 24 months |
Countries
China
Contacts
Primary ContactTian'an Jiang, Phd
Backup ContactGuo Tian, Master
Outcome results
None listed