Water Intervention for Thinking in Kids (WITiKids ) Study

The Effects of Hydration on Brain, Cognition, Memory & Achievement in Childhood

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02816450

Acronym

WITiKids

Enrollment

Registered

2016-06-28

Start date

2014-06-30

Completion date

2018-06-30

Last updated

2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Fluid Intake, Chronic

Keywords

Water, Children, Cognition, Hydration

Brief summary

The aim of this study is to determine the influence of changes in water intake on changes in cognitive function among preadolescent children. Further, the proposed work will determine the relationship between urinary markers of hydration process and cognitive function. We hypothesize that an increase in water intake will result in greater cognitive performance. In addition, improvements in hydration demonstrated by lower urine concentration will be correlated with greater cognitive performance.

Interventions

BEHAVIORALWater Intake

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

9 Years to 10 Years

Healthy volunteers

Yes

Inclusion criteria

1. Parental/guardian consent 2. Normal or corrected-to-normal vision based on the minimal 20/20 standard in order to complete the cognitive task (below 20/20 vision).

Exclusion criteria

1. Participants younger than 9 years and older than 10 years at the time of testing age. 2. Prior diagnosis of cognitive or physical disability, including ADHD (severe asthma, epilepsy, chronic kidney disease, and dependence upon a wheelchair/walking aid). 3. Use of anti-psychotic, anti-depressant, anti-anxiety medication, as well as those medications used for ADD/ADHD (use of any anti-psychotic, anti-depressant, anti-anxiety, and ADD/ADHD medications). 4. Participants must have not yet reached, or be in the earliest stages, of puberty, as measured by a modified test of the Tanner Staging System 5. IQ below 85 6. Use of medications that alter urinary excretion and water metabolism 7. Use of internal electronic device, such as a pacemaker

Design outcomes

Primary

Measure	Time frame
Flanker Task Accuracy	2 Hours on the morning of Day 5

Secondary

Measure	Time frame
Urine Osmolality	24 hours during final day of fluid intake modulation (Day 4)

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026