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Opioid Analgesic Use and Disposal Following Outpatient Dental Surgery

Opioid Analgesic Use and Disposal Following Outpatient Dental Surgery

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02814305
Enrollment
79
Registered
2016-06-27
Start date
2015-03-31
Completion date
Unknown
Last updated
2016-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opioid Use Disorders, Tooth Extraction Status Nos

Brief summary

Background: Overdose deaths from prescription opioid analgesics quadrupled from 4,000 cases to nearly 17,000 cases annually during 1999-2011. Most people who misuse or abuse prescription opioids obtain these pills from friends or family members who have surplus medication left over from prior prescriptions. There is little published data on surplus opioid analgesics remaining after patients recover from painful procedures. Even less is known about patients' willingness to dispose of these leftover pills. Aims: 1) Measure the impact of a risk education intervention and a financial incentive intervention on patients' willingness to dispose of surplus opioids left over after outpatient dental surgery. 2) Measure the number and proportion of opioid pills left unused after outpatient dental surgery. Methods: The study will be a pilot randomized controlled trial. Adult patients at the Penn Dental Care Center will be enrolled prior to elective outpatient dental surgery. Patients will be randomized to a control group, an educational intervention, or a financial incentive intervention. The primary outcome of the trial is the proportion of patients in each arm that express willingness to return their unused opioids. Secondary outcomes include patient use of prescribed opioids and their number of unused pills. These outcomes will be measured using novel text-message based data collection software that patients will interact with using a web-enabled cellular telephone or tablet.

Interventions

BEHAVIORALFinancial

Patient receives information on a program that may offer a financial benefit for disposing of unused opioid analgesics at a pharmacy

BEHAVIORALEducational

Patient watches a video featuring narrative vignettes of patients who developed opioid dependence or abuse after using opioids postoperatively

Sponsors

University of Pennsylvania
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Non-institutionalized

Exclusion criteria

* pregnancy * a history of opioid analgesic misuse/abuse * ongoing participation in other clinical research * or daily use of opioid analgesics in the week prior to surgery

Design outcomes

Primary

MeasureTime frameDescription
Unused opioids21 days after surgeryNumber of opioids reported unused by the patient after postoperative day 21

Secondary

MeasureTime frameDescription
Intent to dispose of opioidsAny time during the 21-day data collection period or during the follow-up interview on (or shortly after) postoperative day 21Patient reports intent to dispose of leftover opioids during follow-up interview or by calling study hotline

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 12, 2026