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Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02814188
Enrollment
37
Registered
2016-06-27
Start date
2016-06-30
Completion date
2017-09-30
Last updated
2017-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impaired Thermoregulation

Keywords

Exercise

Brief summary

Carbohydrate ingestion, in particular fructose, has been shown in a handful of previous studies to elicit a thermic effect and increase core body temperature after ingestion. Carbohydrate foods and supplements are commonly consumed prior to endurance running competition, including situations where an athlete's ability to dissipate body heat is compromised. Thus, there is some potential for pre-exercise carbohydrate ingestion to have a deleterious effect on body heat regulation in hot and humid environments. Thus, this projects aims to study the effects of pre-exercise carbohydrate ingestion on core body temperature, perceived thermal stress, and perceived exertion during high-intensity running.

Interventions

750 ml of a 13.5% carbohydrate (sucrose) beverage

OTHERPlacebo Beverage

750 ml of an artificially-sweetened beverage

Sponsors

Old Dominion University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Be currently running ≥20 miles per week * Have a projected 5-km maximal effort running time between 16:00-23:00 minutes

Exclusion criteria

* Any gastrointestinal disorders that cause swallowing problems or frequent nausea/vomiting

Design outcomes

Primary

MeasureTime frameDescription
Core Body Temperature80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)Core body temperature will be measured with a ingestible pill thermometer. Readings will be taken during a 60 minute rest period and at 1-km intervals during a 5-km run.

Secondary

MeasureTime frameDescription
Thermal Sensation Scale80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)The Thermal Sensation Scale is a 0-8 numerical rating scale with descriptors of unbearably cold at 0, neutral at 4, and unbearably hot at 8. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.
Feeling Scale80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of very bad at -5, neutral at 0, and very good at +5. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.
Rating of Perceived Exertion80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026