Topical Anesthesia for Removal of Stitches After Total Knee Arthroplasty

Topical Anesthesia With Lidocaine Patch for Removal of Metal Staples After Total Knee Arthroplasty: A Prospective Randomized Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02812602

Enrollment

Registered

2016-06-24

Start date

2016-04-30

Completion date

2016-06-30

Last updated

2016-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metal Staple Removal After Total Knee Replacement

Keywords

Total Knee Replacement, Stitch, Removal, Pain

Brief summary

Lidocaine patch is a safe and effective topical anesthetic agent for removal of metal staples after total knee replacement

Detailed description

This is a double-blind randomised control trial. After informed consent, the patients who undergoes primary total knee replacement will be assigned to either control group or experimental group randomly. The effectiveness and complication will be analysed. If the patients are not medically fit for the study (including contraindications for lidocaine), they will be excluded.

Interventions

DRUGLidocaine patch

Lidocain patch will be applied around the surgical wound about 20 minutes before removal of staples.

DRUGplacebo

Placebo patch will be applied around the surgical wound about 20 minutes before removal of staples.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

50 Years to 100 Years

Healthy volunteers

Yes

Inclusion criteria

1. Males and females, aged 50-100 years 2. The patients who undergo primary total knee replacement (performed by the same surgeon, Dr.Jiang) 3. Clear consciousness 4. No contraindication for staple removal on the post-operative day 7

Exclusion criteria

1. Allergy to lidocaine 2. Patient with second or third degree atrio-ventricular block 3. Patients with severe Sinoatrial node block 4. Patients taking class I antiarrhythmia drugs 5. Pregnant patients 6. Patients undergoing revision total knee replacement 7. Contraindication for removal of staples on post-operative day 7

Design outcomes

Primary

Measure	Time frame	Description
Visual analog scale for pain	30min	The person who removes the staples evaluated the pain intensity. The pain intensity is evaluated with visual analog scale for pain

Secondary

Measure	Time frame	Description
Complication rate of lidocaine patch	Two weeks	The incidence of related complications after application of lidocaine patch

Countries

Taiwan

Contacts

Primary ContactTzu-Hao Tseng

b92401004@gmail.com886-978326537

Backup ContactChing-Chuan Jiang

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026