The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal Endoscope

A Clinical Analysis of Scopolamine Hydrobromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02811341

Enrollment

122

Registered

2016-06-23

Start date

2014-08-31

Completion date

2015-06-30

Last updated

2016-06-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Using Copolamine Butylbromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination

Keywords

Scopolamine butylbromide PCLE

Brief summary

Scopolamine butylbromide might be helpful for the outcome of superior gastrointestinal endoscope examination.

Detailed description

The peristalsis of gastrointestinal tract has a adverse affection on the process of the PCLE examination .Scopolamine butylbromide is a widely used spasmolytic，which can reduce the peristalsis of gastrointestinal tract effectly.The application of it may benefit the images'quality ,the acurrate of diagnosis and shorten the examination time.

Interventions

DRUGScopolamine Hydrobromide

DRUGnormal saline

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* outpatients attending endomicroscopy * able to give written informed consent

Exclusion criteria

* coagulopathy * acute upper digestive tract bleeding * pregnancy or breast feeding * allergy to fluorescein sodium * impaired renal function

Design outcomes

Primary

Measure	Time frame
endomicroscopic image quality	7months

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026