Attention Deficit Disorder With Hyperactivity
Conditions
Brief summary
This noninterventional study will assess genomic changes in the metabotropic glutamate receptor (mGluR) network in children and adolescents with ADHD.
Detailed description
Male and female subjects 6 to 17 years of age with a primary psychiatric diagnosis of ADHD will be enrolled in this study. The subject and his or her parent/guardian must agree to genotyping to determine whether the subject has disruptive mutations within any of the approximately 274 mGluR-network genes, and complete an interview that will include information about the subject's ADHD history, treatment, and co-morbidities.
Interventions
None listed
Sponsors
Aevi Genomic Medicine, LLC, a Cerecor company
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
6 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* The subject is male or female ≥6 and ≤17 years of age. * The subject has ADHD as defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition. * The subject, his or her legally responsible representative, and investigator agree to complete ADHD history, treatment, and comorbidity electronic case report form (eCRF).
Exclusion criteria
* The subject or parent/legal guardian is in the opinion of the investigator mentally or legally incapacitated and unable to provide informed consent/assent for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of mGluR network mutations | At study enrollment |
Countries
United States
Outcome results
None listed