Mass Spectral Fingerprinting in Obstructive Sleep Apnoea

Diagnosis of Obstructive Sleep Apnoea by Selective Secondary Electrospray Ionization - Mass Spectrometry (SESIMS)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02810158

Enrollment

150

Registered

2016-06-22

Start date

2016-06-30

Completion date

2018-05-31

Last updated

2018-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exhaled Breath, Mass Spectrometry, Obstructive Sleep Apnoea (OSA)

Brief summary

To answer the question whether a previously detected breath profile in patients suffering from obstructive sleep apnoea (OSA) can be found in a cohort of patients with suspected OSA using mass spectrometry (validation study).

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Clinical suspicion of obstructive sleep apnoea syndrome (based on clinical symptoms such as increased daytime sleepiness; Epworth Sleepiness Score (ESS) \> 10). * Age between 18 and 85 years at study entry.

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
OSA-specific mass spectrometric pattern of VOCs in the exhaled breath	one hour, single measurement, no follow-up	Concentration of volatile organic compounds (VOCs) in the exhaled breath will be analysed using mass spectrometry

Countries

Switzerland

Outcome results