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Microalbuminuria Predicting CIAKI After CAG

Pre-existing Microalbuminuria Predicting Contrast-induced Acute Kidney Injury (CIAKI) Following Coronary Angiography (CAG)

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02808845
Acronym
MPCC
Enrollment
800
Registered
2016-06-22
Start date
2016-12-31
Completion date
Unknown
Last updated
2016-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contrast-induced Acute Kidney Injury, Microalbuminuria

Keywords

coronary angiography, contrast-induced acute kidney injury, microalbuminuria

Brief summary

The purpose of this study is to investigate the association between pre-existing microalbuminuria and contrast-induced acute kidney injury (CIAKI) following coronary angiography (CAG).

Interventions

OTHERmicroalbuminuria

Sponsors

The First Affiliated Hospital with Nanjing Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with eGFR≥30ml/min and without macroalbuminuria undergoing CAG.

Exclusion criteria

* Pregnancy * Lactation * Allergic history of contrast media * Having been received contrast media within 7 days * Use of nephrotoxic medications within 7 days * eGFR \<30 ml/min, macroalbuminuria (ACR \>300 mg/g) * Renal transplantation, emergent coronary angiography * Cardiogenic shock, pulmonary edema * Use of intra-aortic balloon pump (IABP) or mechanical ventilation * Multiple myeloma and other malignant tumor * Life expectancy less than 12 months

Design outcomes

Primary

MeasureTime frameDescription
changes of serum creatinine (SCr, umol/L)24-48 hours after CAGthe difference of SCr before and after CAG.
number of participants with increase in SCr of at least 44.2 umol/L higher than before24-48 hours after CAGnumber of participants with the difference of SCr before and after CAG over 44.2 umol/L.
number of participants with increase of SCr over 25% higher than before24-48 hours after CAGnumber of participants with an increase of SCr over 25% higher than before.

Secondary

MeasureTime frameDescription
changes of urine albumin to creatinine ratio (ACR, mg/g)24-48 hours after CAGthe difference of ACR before and after CAG

Countries

China

Contacts

Primary ContactZhijian Yang, Doctor
zhijianyangnj@njmu.edu.cn+86 13809030208
Backup ContactHaoyu Meng, Master
15805167259@163.com+86 15805167259

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026