Cerebral Palsy
Conditions
Keywords
Cerebral Palsy,, Upper limb neurorehabilitation, Upper Extremity, Neurological Rehabilitation
Brief summary
This 3-year research project aims to investigate and compare the immediate and long-term treatment effectiveness as well as motor improving curve and potential predictors of the unimanual intensive training and bimanual intensive training protocols with an equivalent intervention period in children with hemiplegic CP and children with CP with apparently one side affected. In addition, based on the ICF-CY model, comprehensive outcome measures including motor functions as well as psychological functions will be included.
Interventions
OTHERunilateral upper limbs intensive training
The unimanual intensive training group focuses on the training of the more affected arm and restraint the less affected arm.
OTHERbilateral upper limbs intensive training
The bimanual intensive training focuses activities that required the use of both hands.
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
3 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
The inclusion criteria of this study are: 1. aged between 3 and 16 years 2. diagnosed with congenital hemiplegic or children with CP with one more affected side; (3) apparently disuse phenomenon of the more affected hand at spontaneous contexts Participants will be exclude for: 1. excessive muscle tone (Modified Ashworth Scale ≤ 2 at any joints of the upper limb) before beginning treatment (Bohannon & Smith, 1987) 2. severe cognitive, visual, or auditory disorders according to medical documents, parental reports, and the examiner's clinical observation 3. injections of botulinum toxin type A or operations on the UE within 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes from muscle strength | baseline, week 8, week 24 | Measured by Electromyography (EMG) |
| Changes from String Beads Test (SBT) | weekly test (from baseline to week 8) | — |
| Changes from Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2) | baseline, week 4, week 8, week 24 | — |
| Performance changes assessed by Kinematics Analysis | baseline, week 8, week 24 | Kinematic Analysis including parameters of endpoint control, inter-joints coordination, and trunk involvement, we will analyse children's performance changes from performing reaching tasks |
| Changes from Melbourne Assessment 2 (MA-2) | baseline, week 4, week 8, week 24 | — |
| Changes from Pediatric Motor Activity Log-Revised (PMAL-R) | baseline, week 4, week 8, week 24 | — |
| Changes from ABILHAND-Kids | baseline, week 4, week 8, week 24 | — |
| Changes from Test of Playfulness (ToP) | week 1, week 4, week 5, week 8 | — |
| Changes from Box and Block Test (BBT) | weekly test (from baseline to week 8) | — |
| Changes from Engagement Questionnaire (EQ) | weekly test (from week 1 to week 8) | — |
| Changes from Satisfactory Questionnaire (SQ) | baseline, week 4, week 8, week 24 | — |
| Changes from Building Tower Test (BTT) | weekly test (from baseline to week 8) | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes from Cerebral Palsy Quality of Life Questionnaire for Children (CPQOL) | baseline, week 4, week 8, week 24 |
| Changes from Parenting Stress Index-Short Form (PSI-short) | baseline, week 4, week 8, week 24 |
| Changes from Pediatric Evaluation of Disability Inventory (PEDI) | baseline, week 4, week 8, week 24 |
Countries
Taiwan
Contacts
Primary ContactTien-Ni Wang
Outcome results
None listed