Lung Diseases
Conditions
Keywords
Respiratory Function Tests, Air pollution, Pregnancy, Spirometry
Brief summary
A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy
Detailed description
A single group of 120 pregnant women separated in smokers (n = 17) and nonsmokers (n = 103) and first pregnancy (n = 54) or multiparous (n = 66) who underwent pulmonary function test and used the individual passive sampler in the first and third trimesters of pregnancy
Interventions
PROCEDURELung function test
Pregnant woman use the individual passive sampler 15 days before the spirometry test at each trimester
Sponsors
University of Sao Paulo General Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
15 Years to 41 Years
Healthy volunteers
Yes
Inclusion criteria
* prior informed consent; * single pregnancy; * topical and feasible; * gestational age of less than 13.86 weeks at the first evaluation; * absence of preexisting maternal diseases
Exclusion criteria
* withdrawal from the project; * abortion; * inadequate pulmonary function test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of air pollution in the spirometry of 120 pregnants, evaluated by individual passive samplers in the first (T1) and third (T3) trimesters of pregnancy, using the non-parametric analysis for repeated measures | Through study completion, an average of 3 year |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the influence of smoking and parity and the results of spirometry of all pregnants exposed to pollution comparing the frequency of events held by Wilcoxon and the Mann Witney test | Through study completion, an average of 3 year |
Outcome results
None listed