TNF Polymorphism and Implantation Rate

Tumor Necrosis Factor-308 Polymorphism a Embryo Implantation Rate in Women Undergoing in Vitro Fertilization

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02806934

Enrollment

120

Registered

2016-06-21

Start date

2009-06-30

Completion date

2013-12-31

Last updated

2016-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

Detailed description

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Interventions

PROCEDUREbiological and ultrasound test

biological and ultrasound test 20 days after implantation in order to see the implantation rate

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 37 Years

Healthy volunteers

Inclusion criteria

* Women * normal karyotype, * age under 38 years * serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l

Exclusion criteria

* age under 18 years

Design outcomes

Primary

Measure	Time frame
Implantation rate by biological test	20 days after implantation
Implantation rate by ultrasound test	20 days after implantation

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026