Anesthesia
Conditions
Brief summary
This prospective study aimed to determine the minimal level of Bispectral index needed for quality laryngoscopy before ear, nose and throat surgery in children.
Detailed description
* Children will received intra-rectal premedication based on midazolam 0.4mg * Children will be monitored according to standard guidelines * One blinded anesthesiologist will be in charge of anesthesia induction and the other one will be in charge of data collection (end tidal sevoflurane concentration, sevoflurane minimal alveolar concentration, bispectral index) and guidance of induction according to the predetermined bispectral index (up and down allocation)
Interventions
DRUGSevoflurane
After at least 4 minutes of stable inspired sevoflurane concentration, that concentration will be titrated to obtain a targeted bispectral index (BIS) level required for perform laryngoscopy. This level was initially set at 40, based on a preliminary study showing that such level of BIS was obtained at the laryngoscopy after common general anesthesia induction. For the next patients, BIS target was set according to a sequential allocation method (up and down).
Sponsors
University of Liege
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 8 Years
Healthy volunteers
Yes
Inclusion criteria
* American Society Anesthesiology physical status classification system :1 or 2 * scheduled ear, nose and throat surgery in a one day program * oral intubation required
Exclusion criteria
* parents refusal * recent respiratory infection * epilepsy * suspected difficult intubation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| laryngeal conditions of intubation | 5 minutes | specific conditions will be assessed and scored : jaw relaxation, vocal cord position, cough at intubation |
Outcome results
None listed