Adverse Drug Events
Conditions
Keywords
adverse drug events, preventable, potential, counselling, medication reconciliation
Brief summary
The implementation of a medication reconciliation intervention including: medication reconciliation on admission and discharge, bedside medication counselling and take-home medication list, on the development of adverse drug events within 30 days post discharge as primary outcome. Secondary outcome is the evaluation of its impact on health care resource utilization
Detailed description
This is a randomized controlled trial in 587 patients randomized to intervention and usual care. The intervention is medication reconciliation on admission and discharge, bedside medication counselling and take-home medication list. Usual care is ward pharmacy practice. The primary outcomes are preventable and potential adverse drug events at 30 days post discharge. The secondary outcome is health care utilization: length of stay, emergency room visits, unplanned hospital visits, readmissions and travel abroad to seek medical attention.
Interventions
OTHERmedication reconciliation intervention
medication reconciliation intervention comprises medication reconciliation on admission and discharge, bedside medication counseling and take-home medication list
Sponsors
Sultan Qaboos University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* admitted to one of the two medical wards, male and female medical wards. * was on at least one medication prior to admission * spoke Arabic or English and can be (the patient or care giver) interviewed for medication history * stayed in the hospital for at least 24 hours * discharged on at least one chronic medication or is at least on one chronic medication even if not prescribed upon discharge
Exclusion criteria
* could not be interviewed due to language barrier, impaired cognition or other reasons and did not have a care giver * was under specialties other than medical specialties, but was admitted to medical wards because of lack of beds in their respective wards * was pregnant * was already included in the study at a previous admission * left the hospital against medical advice * with length of stay of \>60 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| number of patients with a preventable adverse drug event | 30 days |
| number of potential adverse drug events | 30 days |
Secondary
| Measure | Time frame |
|---|---|
| number of emergency room visits | 30 days |
| number of unplanned hospital visits | 30 days |
| number of hospital readmissions | 30 days |
| number of patients who traveled abroad to seek second medical opinion | 30 days |
Outcome results
None listed