Primary Open- Angle Glaucoma
Conditions
Brief summary
This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele.Primary open-angle glaucoma patients and age-matched people in the Han population were enrolled. Vitamin D receptor polymorphic analysis was studied by polymerase chain reaction-restriction fragment length polymorphism technique.
Interventions
Sponsors
Tianjin Medical University Eye Hospital
Lv Yingjuan
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
55 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* intraocular pressure greater than 22 mmHg with two or more medications wide anterior chamber angle glaucomatous optic neuropathy (Glaucomatous optic nerve damage was defined as cup-to-disc ratio higher than 0.7 or focal loss of the nerve fiber layer (notch) associated with a consistent glaucomatous visual field defect) visual field loss consistent with optic nerve damage and visual fields were performed by using standard automated perimetry
Exclusion criteria
* the presence of any secondary glaucoma including exfoliation syndrome or a history of ocular trauma high myopia macular degeneration other ocular diseases a known history of systemic diseases and administration of vitamin D3 or other analog
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gene polymorphisms of vitamin D receptor | 1 day visit |
Countries
China
Outcome results
None listed