Evaluation of the Alveolar Recruitment Obtained During Non-invasive Ventilation After Cardiac Surgery

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02804997

Acronym

ARCTICS

Enrollment

Registered

2016-06-17

Start date

2015-05-13

Completion date

2017-01-27

Last updated

2018-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Surgery

Keywords

non-invasive ventilation, cardiac surgery

Brief summary

The great majority of cardiac surgery patients develop a degree of post-operatory respiratory failure. This is due to several factors. The predominant element in the onset of this respiratory impairment is the constitution of foci of pulmonary atelectasis, caused by peroperative hypoventilation (in the presence or absence of ECC). The incidence has been evaluated at between 54% and 92%, depending on the study. The use of NIV (non-invasive ventilation) might (through the application of continuous positive expiratory pressure) help to counter the development of these atelectasic foci.

Interventions

None listed

Study design

Observational model

CASE_CROSSOVER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥18 * in the post-operative phase after elective cardiac surgery for aortic or mitral valve replacement, coronary revascularization or mixed surgery, hypoxemia or hypercapnia, with an indication for NIV, * hemodynamic stability * prior consent * spontaneous ventilation * social security coverage.

Exclusion criteria

* Under-18 patients * complex cardiac surgery * pregnancy * pre-existing chronic obstructive respiratory disease (COPD \> stage II) * legal guardianship * incarceration

Design outcomes

Primary

Measure	Time frame	Description
Quantitative evaluation by thoracic CT scan	3 hours	Quantitative evaluation performed by thoracic CT scan of alveolar recruitment induced by NIV after cardiac surgery

Countries

France

Outcome results