Physiopathological and Therapeutic Value of microRNA in the Progression of Carotid Artery Plaques: Carotid Protocol and microRNA

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02804659

Acronym

CAMIA2

Enrollment

Registered

2016-06-17

Start date

2015-03-26

Completion date

2018-02-26

Last updated

2026-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Arteries

Keywords

micro-RNA

Brief summary

Molecular analysis of the atheroma plaque. Screening for a novel biomarker of carotid status.

Interventions

OTHERmicroRNA

Extraction of the microRNA using the mirVana miRNA isolation kit and quantification using real-time PCRs

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults having to undergo carotid thromboendarteriectomy * social security coverage * provision of study information * consent to participation.

Exclusion criteria

* Previous carotid artery surgery * refusal to participate in the study * or inability to give consent.

Design outcomes

Primary

Measure	Time frame	Description
expression level of the seven miRNAs of interest	Day of surgery	expression level of the seven miRNAs of interest in the serum and in carotid artery plaques : miR-100, miR-125a, miR-127, miR-133a, miR-145, miR-221

Countries

France

Contacts

PRINCIPAL_INVESTIGATORPierre MAITRIAS, PhD

CHU Amiens

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 13, 2026