Aphasia Therapy: Factors of Efficacy

Constraint Induced Aphasia Therapy in Stroke Patients in Acute Stage.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02804412

Enrollment

Registered

2016-06-17

Start date

2005-03-31

Completion date

2013-03-31

Last updated

2016-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aphasia

Keywords

communication disorders, language and speech disorder rehabilitation, stroke

Brief summary

Constraint-induced aphasia therapy (CIAT) has proven effective in stroke patients. It has remained unclear, however, whether intensity of therapy or constraint is the relevant factor. This study will give an answer to this question to improve speech and language therapy.

Detailed description

Although there is clear evidence that aphasia therapy is effective, questions remain as to the intensity of administered therapy, the preferred therapeutic approach and its initiation with regard to stroke onset. CIAT is a a high intense group therapy administered over 2 weeks. Additionally, patients have to communicate solely in spoken words or sentences (constraint). This study compares CIAT with an approach of the same intensity without constraints and a less intense house-typical therapeutic approach.

Interventions

OTHERControl group

This is the control group with 14 h treatment over 10 workdays.

OTHERCIAT-group

Examine the efficacy of CIAT (30 h over 10 workdays) versus Control-group and communication treatment group.

OTHERcommunication treatment group (CTG)

Examine the efficacy of CTG (30h over 10 wokrdays) versus CIAT-group and control group

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

39 Years to 89 Years

Healthy volunteers

Inclusion criteria

* first ever stroke * suffering from aphasia

Exclusion criteria

* severe cognitive or attentional impairments * severe depression * left-handedness * severe dysarthria * apraxia of speech * severe deafness * additional neurological diseases affecting speech (e.g. Parkinson's disease)

Design outcomes

Primary

Measure	Time frame
Change of aphasia by Aachener Aphasia Test (AAT)	pretreatment and within 24 h post intervention

Secondary

Measure	Time frame	Description
Change of Communication Activity Log (CAL)	pretreatment and within 24 h post intervention	The CAL is a two-part questionnaire rating the amount and the quality of daily communication on a six-point scale

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026