Acute Appendicitis
Conditions
Keywords
peritoneal closure, appendectomy, postoperative pain, life quality
Brief summary
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.
Detailed description
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. in literature, few reports suggested that peritoneal closure may prolong the operation time, may increase the costs and has a probable aggravating effect on postoperative pain. In addition, there have been some reports that suggest non closure of peritoneum may not increase the postoperative complications. The need of further studies to clarify the effect of peritoneal closure versus non closure on postoperative pain and life quality especially has been specified in some literature. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.
Interventions
PROCEDUREopen appendectomy with peritoneal closure
open appendectomy with peritoneal closure under general anesthesia for acute appendicitis
PROCEDUREopen appendectomy without peritoneal closure
open appendectomy without peritoneal closure under general anesthesia for acute appendicitis
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* patients with acute appendicitis * age between 18-65 years
Exclusion criteria
* preoperatively diagnosed intraabdominal abcess * intraoperatively diagnosed free purulent fluid in abdominal cavity * pregnancy * malignancy history * mental retardation * chronical renal failure * chronical liver disease * diabetes mellitus * patients' denial of participation to study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue pain score | postoperative day 1 | visual analogue score for pain at postoperative day 1 via using 10 cm vas scale. |
| Surgical Site Infection | postoperative 30 days | Postoperative Surgical Site Infection in 30 days following surgery includes incisional infections and intrabdominal abcess |
| Life Quality Score | postoperative day 10 | Euro-Qol 5D-5L for assesment of life quality at postoperative day 10th |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| operation time | intraoperatively | time from beginning of incision to closure of incision |
| wound dehiscence | postoperative 30 days | fascial dehiscence during postoperative 30 days diagnosed via physical examination of sonography. |
| postoperative mortality | postoperative 30 days | mortality in postoperative 30 days |
Countries
Turkey (Türkiye)
Outcome results
None listed