Hypotension
Conditions
Keywords
Hypotension, cesarean section
Brief summary
The purpose of this study is to compare the frequency of hypotension between hyperbaric anesthetics and isobaric anesthetics during cesarean section and determine whether continuous infusion of phenylephrine is effective in mothers who received hyperbaric anesthetics.
Interventions
DRUGBupivacaine
spinal anesthesia with hyperbaric bupivacaine
DRUGLevobupivacaine
spinal anesthesia with isobaric levobupivacaine
DRUGPhenylephrine
continous infusion of phenylephrine
DRUGnormal saline
continous infusion of normal saline
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* pregnant woman scheduled for elective cesarean delivery under spinal anesthesia
Exclusion criteria
* patients who refuse involved * patients who have pre-eclampsia * patients who have heart disease * patients who fetal distress is suspicious
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of hypotension events with treatment related | during 30min after spinal anesthesia | blood pressure was obtained every 1min. A 20% decrease or more decrease in SAP compared to baseline was considered as hypotension. Hypotensive events during first 30 min was recorded as primary outcome. |
Secondary
| Measure | Time frame |
|---|---|
| total dose of phenylephrine | during the surgery |
Countries
South Korea
Outcome results
None listed