Effect of Left Atrial Ablation on Left Atrial Appendage Emptying Flow Velocity

Differential Effect of Radiofrequency and Cryoballoon Ablation on Left Atrial Appendage Emptying Flow Velocity

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02801175

Acronym

ABLAA-FV

Enrollment

Registered

2016-06-15

Start date

2016-05-31

Completion date

2017-03-31

Last updated

2016-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Brief summary

Consecutive patients with paroxysmal AFib scheduled to undergo pulmonary vein isolation either with radiofrequency (RF) or cryoballoon will be included. Left atrial appendage emptying flow velocity (LAA-EFV) will be measured with transesophageal echocardiography (TEE) immediately before and following left atrial ablation (1 month post). The change in LAA-EFV will be compared between the two groups (RF versus Cryo).

Interventions

PROCEDUREPulmonary vein isolation

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 85 Years

Healthy volunteers

Inclusion criteria

Paroxysmal atrial fibrillation, no absolute contraindication for anticoagulation

Exclusion criteria

Previous cardiac surgery Previous left atrial ablation History of cerebrovascular event Presence of LAA thrombus Inability to provide informed consent

Design outcomes

Primary

Measure	Time frame	Description
LAA-EFV	1 month	Left atrial appendage emptying flow velocity

Secondary

Measure	Time frame	Description
LAA-EFV	3 months	Left atrial appendage emptying flow velocity

Countries

Greece

Contacts

Primary ContactSpyridon Deftereos, MD

spdeftereos@med.uoa.gr2105832352

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026