Pancreatic Duct Cannulation During Endoscopic Retrograde Choledochopancreatography
Conditions
Keywords
pancreatic duct, ERCP, acetic acid
Brief summary
Intraduodenal acetic acid can stimulate secretion of water and bicarbonate from pancreatic ductal cells. In this study, acetic acid spraying to duodenal bulb was compared with saline solution for the facilitation of pancreatic duct cannulation in patients.The primary outcome was successful deep pancreatic duct cannulation. The secondary outcomes were the appearance of the major and minor papillary orifice, pancreatic juice flow from the papilla, time to achieve deep pancreatic duct cannulation, and fluoroscopy time for deep pancreatic duct cannulation in the acetic acid group versus saline group.
Interventions
DIETARY_SUPPLEMENTacetic acid
DIETARY_SUPPLEMENTsaline
Sponsors
Changhai Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Inclusion criteria were(1)those with intact native papilla (2)who underwent endoscopic retrograde choledochopancreatography for pancreatic duct, (3)age≥18 years，≦80years,and (4)agreement to participate in the study.
Exclusion criteria
*
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cannulation time for deep pancreatic duct cannulation | 2 days |
| fluoroscopy time for deep pancreatic duct cannulation | 2 days |
Secondary
| Measure | Time frame |
|---|---|
| pancreatic juice flow from the major papilla | 2 days |
| appearance of the major papillary orifice | 2 days |
Countries
China
Outcome results
None listed