Odontoid Fracture, Osteoporosis, Surgery
Conditions
Brief summary
Usually, cervical spine fractures are not considered as osteoporotic fractures. However, recent studies show that odontoid fractures are the most common fractures of the cervical spine in elderly and may occur in a context of low trauma energy. Thus, the goal of this observationnal study is : * to describe the different type of odontoid fracture and to characterize bone status in elderly patient (\>65 y) who underwent odontoid fracture in a context of low trauma energy. * To describe short and long term outcomes
Detailed description
All patients over 65 y admitted for low trauma odontoid fracture will be consecutively included in the study after informed consent. The investigators will record: * clinical risk factor of osteoporosis and health habits including accomodation * type of fracture and characterization of the odontoid fracture on imaging (standard X ray / MRI / QCT) * Bone status : bone mineral density on DXA, lab tests for secondary osteoporosis check-up, previous vertebral fracture on VFA or X ray * osteoporosis managment : nutrition, vitamin D, anti-osteoporotic drugs * treatment of the fracture : surgical / non surgical * adverse event during hospitalization * lenght of hospital stay * type of discharge Follow-up à 3 and 12 months : dead vs alive ; accomodation ; autonomy ; new fracture
Interventions
OTHERobservational
describe bone status and outcome of odontoid fracture
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all patients over 65 y admitted for low traumat odontoid fracture
Exclusion criteria
* patient \< 65 y * traumatic odontoid fracture
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone status at the time of odontoid fracture: bone mineral density, prevalent osteoporotic fracture, vitamin D status | from date of inclusion until to 3 weeks after the event. Inclusion will be proposed within 2 weeks after the fracture | clinical risk factor of osteoporosis, prevalent clinical osteoporotic fracture, bone mineral density measured by DXA, vertebral fracture assessment to detect other vertebral fracture, serum concentration in 25OHvitamin D |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| mortality | during hospitalization - 3 and 12 months after inclusion | mortality after odontoid fracture during hospitalization and at 3 and 12 monts |
| morbidity | during hospitalization - 3 and 12 months after inclusion | incident osteoporotic fracture, adverse event such as infection, cardiovascular event, neurological event |
| loss of autonomy | discharge, 3 and 12 months | lenght of hospital stay, type of discharge (home, nursing home, rehabilitation bed care, institutionalized accomodation |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORveronique breuil, MD, PhD
Centre Hospitalier Universitaire de Nice
Outcome results
None listed