Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02799134

Acronym

NMCARSEHHSC

Enrollment

Registered

2016-06-14

Start date

2015-11-30

Completion date

2017-04-30

Last updated

2022-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

Cortisol Awakening Response suppression, Dexamethasone Suppression Test, high-order cognition, social cognition

Brief summary

CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...

Interventions

DRUGDexamethasone

DRUGVitamin C

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

BASIC_SCIENCE

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

MALE

Age

18 Years to 26 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy college students.

Exclusion criteria

* Current or history of psychiatric or neurological illness. * Current use of any medications.

Design outcomes

Primary

Measure	Time frame	Description
Cortisol Awakening Response Level(nmol/L) after Taking Dexamethasone	one year	The dosage of Dexamethasone is 0.5mg.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026